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🥝 [50006078-RSE3A] Senior Scientist I, Food & Nutrition

A*STAR - Agency for Science, Technology and Research | singapore, Singapore | Posted June 24, 2026

Job Description

Key Responsibilities

  • Lead development and optimisation of GPCR functional assays, including reporter‑based systems (e.g., luciferase, cAMP, calcium, β‑arrestin readouts) suitable for medium‑ to high‑throughput screening.
  • Develop new reporter systems for additional functional or phenotypic endpoints beyond GPCR signalling.
  • Design, generate, and validate stable or transient mammalian reporter cell lines, including construct design, molecular cloning, and cell line engineering.
  • Collaborate with cross‑functional teams (e.g., chemistry, computational biology, screening teams) to support compound evaluation and mechanistic studies.
  • Analyse and interpret experimental data, including dose‑response relationships, assay performance metrics, and screening outputs.
  • Prepare scientific reports, presentations, and publications, and maintain rigorous documentation of experimental workflows.
  • Supervise and train junior sta...

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