The Morscher Laboratory works at the intersection of pediatric oncology and fundamental research in metabolism. Stable isotope tracing is a core methodology of the lab - applied across cell culture, animal models, and directly in patients to map metabolic fluxes at quantitative resolution. We combine this with single-cell metabolomics, RNA mass spectrometry, and proteomics to decode metabolic programs from the whole organism down to the single cell - and to translate these insights into new treatment strategies for children with cancer.