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🥝 Protein Principal Scientist

Substrate Bio | london, United-Kingdom | Posted June 06, 2026

Job Description

The opportunity

Substrate is building a network of fully autonomous wet labs, cloud-based data production facilities for AI biology, integrated with foundation models to become the critical infrastructure layer for AI-driven biological discovery. Our first node opens in King’s Cross, London, with several integrated workcells and two scientific verticals online by mid‑2027. Our customers range from foundation model labs to global pharma.

Protein science is the first scientific vertical we are bringing online. The vertical covers expression and purification, biophysical characterisation, cell-based functional assays, and developability assays. Manual development of the day‑1 assay menu is starting now, and full autonomous execution on workcells is targeted for mid‑2027. You and the Protein Scientist will be the bench scientists who develop, validate, and operate the assays through that transition: running protocols by hand, setting reproducibility and quality thre...

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