SUMMARY/JOB PURPOSE:
The Senior Scientist II of preclinical bioanalysis provides preclinical bioanalytical support for the advancement of the biologics portfolio at Exelixis. The incumbent must have strong LCMS-based bioanalysis experience as s/he supports preclinical activities of ongoing and new projects in antibody drug conjugates and other biologics.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
Independently design and execute assay development and qualification of ADCs or other biologics in rodent and NHP matrices, perform pharmacokinetic sample analyses in support of proof-of-concept studies on biologic oncology programs from discovery to lead selection.
Design, implement and manage studies for pharmacokinetic characterization of biologic drug candidates conducted by CROs and in-house as needed.
Critical scientific/technical data analysis and interpretation of experiments.
Interact and collaborate wi...